My Healing CommunityIntegrative Oncology Field Guide

Lung Cancer

Evidence-based overview of mebendazole in lung cancer, including ERK relevance and broader signalling interest

Mebendazole has meaningful mechanistic relevance in lung cancer, especially in tumours driven by ERK / MAPK and survival-pathway signalling.

Overview

The current note set here is more mechanism-driven than trial-driven, but lung cancer remains an important fit for mebendazole because of ERK, angiogenesis, and resistance-related biology.

Key findings

  • ERK / MAPK signalling is frequently upregulated in NSCLC

  • Mebendazole's pathway effects suggest relevance in proliferation, spread, and resistance contexts

  • Combination strategies are likely to matter more than monotherapy in high-ERK disease

Clinical positioning

This remains an emerging fit rather than a fully developed clinical one, but it is a reasonable page to keep in the structure.

References

Mebendazole as a Candidate for Drug Repurposing in Oncology
https://pmc.ncbi.nlm.nih.gov/articles/PMC6769799/

This information is for education only. It is not medical advice, diagnosis, or treatment. Please speak with a qualified clinician before making changes to care, medication, or supplement use.

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