Head & Neck Cancer
Evidence-based overview of curcumin in head and neck cancer, including mucositis support and anti-metastatic findings
Curcumin has supportive-care and direct anticancer relevance in head and neck oncology.
Overview
This is one of the more clinically meaningful areas for curcumin because the literature includes patient-relevant supportive care, especially around radiotherapy.
Key findings
Human studies suggest curcumin may reduce the severity of radiation-induced mucositis
Oral cancer models show anti-EMT and anti-metastatic effects
Curcumin's anti-inflammatory effects are especially relevant in this setting
Practical interpretation
Head and neck cancer is a strong example of curcumin being relevant not only for tumour biology but also for treatment tolerability and quality of life.
References
Efficacy of curcumin in the prevention and treatment of radiotherapy-induced mucositis in head and neck cancer patients
https://pubmed.ncbi.nlm.nih.gov/23136625/
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