Breast Cancer Pathways Free to Download Worksheets

Welcome to the latest worksheet.
Released in June 2021 and updated on a regular basis.

Our creation of these freely shared breast cancer pathway worksheets honors the memory of Lauren, Sarah, and all of our sisters who have passed. These efforts represent our compassion and care for the breast cancer healing community.

Good Sense & Safety First: The information presented in the worksheets should not be taken as medical advice. Please consult a medical practitioner before adding any drug or supplement to your protocol, and seek out guidance from an integrative cancer practitioner who can guide you in your protocol choices.

Collaboration, community & care.

The Breast Cancer Pathways worksheet project began in early 2019 as a collaboration between two stage IV breast cancer thrivers, Maria Wessling Bachteal and Abbey Mitchell. With help from members of our Facebook group, we have dedicated countless hours searching for and organizing breast-cancer-specific laboratory and clinical research that is accessible in the public domain.

We acknowledge our teachers.

The best selling book How to Starve Cancer inspired us to take the many steps needed to better understand the biological mechanisms underlying our breast cancer diagnoses. Visit Jane McLelland’s website to find her online learning support groups and online courses.

Our breast cancer pathways are based on the groundbreaking work of Douglas Hanahan, PhD and Robert A. Weinburg, PhD, whose landmark 2000 paper and subsequent 2011 update outlined the Hallmarks of Cancer, eight biological capabilities acquired during the multi-step development of human tumors as well as introducing other important concepts related to tumor progression. Hanahan further expanded this concept in his 2014 paper “Rethinking the War on Cancer.” 

You’ll find the auto-fill format and many information changes from previous versions. We have broadened the scope to include concepts from the original Hallmarks of Cancer paper and its 2011 update.


What information does the worksheet provide?

Here we present a systematic framework for breast cancer survivors and their clinicians to help organize their current protocol of off-label drugs and supplements based on a summary of available evidence. Cancer is complex, and many of the pathways affect and occur under multiple hallmarks, though we have placed each pathway under one hallmark for simplicity. This is not an exhaustive list of available evidence as many research studies are being added to PubMed and others have yet to be discovered.

The worksheet is meant to be informational and is meant to enhance, not replace, standard-of-care (SOC) and or integrative oncology protocols.

The worksheet should not be viewed as a prescriptive “laundry list” of things to take. Instead, we hope this effort will lead you and your integrative practitioner to further consider the impacts of your protocol and explore the evidence available on the PubMed database.

The worksheet is organized into a set of pages, each representing one of the Hallmarks of Cancer, along with a resources page to further your understanding of the research on integrative approaches to breast cancer treatment.

These pages are:

Manipulate Signaling

Dysregulate Metabolism


Evade Immune System

Achieve Immortality

Avoid Death

Eliminate Cancer Stem Cells


1 minute video preview of the Breast Cancer Pathways Worksheet page titled: Manipulate Signalling.

Cancer doesn’t happen in a vacuum. It’s just as important to consider the environment in which your cancer is growing, so we encourage exploration into areas of your personal terrain that need attention, especially the emotional and environmental contributors.

How many drugs, herbs, and/or nutrients should you take for each category?

The information provided here is not meant to be prescriptive but rather serve as a guide to help you and your integrative cancer practitioner work within the context of your standard-of-care oncology protocol.

The worksheet summarizes research available in the public database PubMed.  The strength of the evidence varies for each pathway and substance.  In many cases, only in vitro (cells studied in the lab) evidence is available and the effects in humans are unknown. 

We encourage users to seek out help from an integrative cancer practitioner to put the research into the context of clinical experience and help you create the best protocol for your individual situation.

Some herbs or nutrients may affect the bioavailability or side effects of certain drugs because of P450 enzyme interactions.  This should be discussed with your integrative cancer practitioner.

Has this information been validated?

Most of the information summarized in the worksheet comes from pre-clinical research, meaning not verified in humans. Because of the lack of financial incentives, human research into the off-label drugs and supplements presented here is rare.

In practice, integrative cancer practitioners use off-label drugs, supplements, and therapies within their comprehensive protocols, in a clinical setting, to improve the effectiveness of conventional treatments.

The practitioners and researchers whose books, presentations, and research articles support the use of these concepts in clinical practice include, but are not limited to, the following (in no particular order) :

Neil McKinney, ND, Keith Block, MD, Daniel Thomas, M.D, Brian Lawenda, MD, Donnie Yance, MH, CN, RH (AHG), Lise Alschuler, ND, FABNO, Dwight McKee, MD, Gurdev Parmar, ND, FABNO, Jason Miller, DACM, LAc, Nalini Chilkov, OMD, LAc, Tina Kaczor, ND, FABNO, Kristin Wohlschlagel RN, Walter Longo, PhD, Dominic D’Agostino, PhD, Daniel Thomas, DO, and Dr Nasha Winters, FABNO

Personal Questions About Your Protocol?

Please show your respect by researching and presenting your personal questions to your cancer study support groups, your integrative doctors and your naturopaths that understand cancer and never message us or tag the breast cancer research project team members directly with your personal healing questions. Perhaps start with a read through the A-Z list of study support threads and files here.

By sharing your questions with your online community, you give other users the opportunity to learn and explore aspects of the worksheet. 


or Here

After you click on the image above you will be brought to a Google sign-in page where you’ll be prompted to sign into your account or create a free G-mail account.

Open your Google drive (you get one free when you create a free G-mail account.)

Make a copy of the Worksheet as you are instructed. e.g

e.g the prompt appears to copy the worksheet

Once your copy of the worksheet is open in Google sheets app.

Add your name and the date to the title of the worksheet.

e.g delete the words “ Copy of” and add your name and note the time period this worksheet will reflect. This title can be changed at any time.

At the bottom of the screen you can see the colored tabs that allow you to navigate your way to each page of the worksheet where you will see your master data menu choices reflected.

e.g of navigation tabs at the bottom of the page

Take a look around your own personal copy of the worksheet.

This 1 minute (silent) video demonstrates how to navigate the worksheet on a desktop using the app’s navigation tools.
Navigating on a Mobile Device is different: You will notice that the worksheet navigation tabs at the very bottom of your screen will hide once you scroll down the page. Scroll up the page and the navigation menu tabs will re-appear. When all navigation tabs and menus vanish click on the little ‘tick’ symbol that appears at the very top left corner of the screen to move out of edit mode and back into navigation mode.

Start using your worksheet by first indicating your current choices using the pull-down menu on the page titled “Enter Master Data”

IMPORTANT: Do not edit our text in Column A or in Column B on any sheet as you will break the code that enables the information to populate the entire worksheet.

You can write what you like in all the other columns to the right side of column B.

This is a quick (under 2 minute) video demonstrating what happens when you indicate what you are either YES taking, considering, been suggested, cycling or only having 1 week in 4.

Where do I add my Standard of Care (SOC) Choices?
Just below the A-Z list of master data items there are blank spaces for all the other items in your protocol. Unfortunately these additions won’t be reflected in the other pages throughout the worksheet. List them here anyway to support your team to see the whole picture.

Typical Dosages?
Be sure to find & bookmark the free worksheet resource titled Typical Clinical Use.
The video below will guide you to the inbuilt links that take you to this resource.

A link to Maria’s Typical Clinical Use notes for all the supplements and repurposed drugs is found near the top of the pages. Simply click on the cell that says Typical Dosages

Sharing your personal worksheet is easy.
Use the SHARE button (top left) to add the email address of your doctor/s or anyone else you want to share your online worksheet with.

A quick screen recording to support anyone who has not shared a Google Worksheet before.
A quick screen recording demonstrates a golden rule: “copy & edit worksheet name before you update master data”.

Want a hard copy?
Download each individual page or “sheet” onto your hard drive in Adobe and put in appropriate page breaks before printing. Do not print directly from a Google drive.

Need technical help?
Google has many tutorials online, and many users have posted their own video tutorials about how to work with Google sheets.

Appreciation, Gratitude and Healthy Boundaries.

We offer special thanks to Steve Cossell, Jayde Simpson, Debbie Hayes, Riki Rose, Arpan Talwar, Sally Cusack, Antonia Keiko Anni and Sheena McKinney for their help with the many editing tasks needed to bring this new worksheet to fruition.

Providing Worksheet Feedback.
Feedback regarding the worksheet is most welcome. Please use this feedback form: Breast Cancer Pathways Worksheet Feedback

Please support the development of this project by sharing your own research finds in the Breast Cancer Pathways study group with hashtags/post topics that match the worksheet segments/pages.

Note that the Pathways Group has tight RULES:
This is a breast cancer research and study group.
Do not post requiring help, support.
Do post information that informs members of research/trials/papers on drugs and supplements and other products that are shown to aid or to avoid in the breast cancer healing journey.
Important: You need to use a hashtag # from this list in order to have your post approved. This list matches the pathways covered in the worksheet and we need the hashtags # entered in order to make the data collection step easier and faster for all concerned.
Pathway group members will find the Hashtag list PDF (click here) within the group files.

HER2+ Breast Cancer – Integrative Protocols facebook group with Maria
is not a typical HER2+ support group, but a HER2+ INFORMATION SHARE group. “We have a base understanding of integrative cancer care from many helpful books and online resources—and understand the role we can play in steering our own HER2+ cancer navigation ship”. In order to join this private HER2+ group you will need to send Maria a friend request and a private message telling her that you or your loved one has a HER2+ breast cancer diagnosis.

HER2+ Breast Cancer – Integrative Protocols facebook group

Healing Cancer Study Support Group

The A-Z list of conversation threads and files found in the healing cancer study support group with Abbey unpacks many of the same supplements and repurposed drugs we have researched for the breast cancer research project worksheets.

Healing Cancer Study Support Group

The healing cancer study support group‘s A-Z directory is helpful in that it takes existing group members directly to a thread of information on the same topic within the Facebook group. Existing conversation threads are the best place to read and ask your questions regarding the worksheet.

Join and participate in these online communities to learn all you can. Please be sure to search the group for keywords that could answer your questions. Take your time and take notes before posting your questions. Many questions have already been asked and answered to some degree. Start with a search before a new post.

In gratitude for our healing community.
Maria and Abbey